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MiR-140-3p is Involved in In-Stent Restenosis by Targeting C-Myb and BCL-2 in Peripheral Artery Disease.

J. Atheroscler. Thromb.. 2018; 
ZhuZheng-Rong,HeQiong,WuWei-Bin,ChangGuang-Qi,YaoChen,ZhaoYang,WangMian,WangShen-
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Catalog Antibody … The mem- branes were blocked with 5% BSA for 1 h, followed by incubation with primary antibodies overnight at 4℃. The membranes were incubated with HRP-con- jugated secondary antibody (A00098, GenScript, USA). The … Get A Quote

摘要

In-Stent Restenosis (ISR) is the major reason for recurrent ischemia and amputation after endovascular treatment of Peripheral Artery Disease (PAD). Our previous study demonstrated that miR-140-3p is significantly down-regulated in PAD arteries. However, expression and function of miR-140-3p in ISR of human PAD are currently unclear.The aim of this study is to determine the miR-140-3p expression and its regulative role in ISR of PAD.

关键词

BCL-2,C-Myb,In-stent restenosis,MiR-140-3p,Peripheral arterial dis